NSF award 2446451 · William Marsh Rice University

Tools4Cells: Development of self-amplifying RNA systems for bacterial protein synthesis

Final report due

29 December 2028

in 803 days · The award ends on 31 August 2028.

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award ending 2028-08-31 · Research.gov
PAPPG 24-1: “at least ten calendar days prior to the end date”
Final report due29 Dec 2028in 803 days
award ending 2028-08-31 · Research.gov
PAPPG 24-1: “no later than 120-days following the end date of the award”
Project outcomes report due29 Dec 2028in 803 days
award ending 2028-08-31 · Research.gov
PAPPG 24-1: “no later than 120 days following the end date”
Award is closed out29 Dec 2028in 803 days
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PAPPG 24-1: “financially closed out 120 days after their expiration date”

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So the final report is due by 29 December 2028.

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Award card

Award number: 2446451
Period of support: 1 Sep 2025 – 31 Aug 2028
Amount: $986,944
Awardee: William Marsh Rice University, Houston, TX
Program: Innovation: Research Methods
Directorate: BIO

Abstract

An award is made to William Marsh Rice University to enable the development of a safe, programmable RNA-based system for transient protein production in bacteria. Harnessing the replicative machinery of single-stranded RNA bacteriophages and incorporating regulatory control elements, this project will produce self-replicating RNA (srRNA) scaffolds that function across a broad range of bacterial species. This…

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