NSF award 2454140 · The Scripps Research Institute

Computer-aided Synthesis and Diversification of a Selective SQR Inhibitor

Final report due

29 December 2028

in 803 days · The award ends on 31 August 2028.

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Decide about an extension3 May 2028in 563 days
award ending 2028-08-31 · Research.gov
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Extension request17 Jul 2028in 638 days
award ending 2028-08-31 · Research.gov
PAPPG 24-1: “at least 45 days prior to the end date”
No-cost extension notice21 Aug 2028in 673 days
award ending 2028-08-31 · Research.gov
PAPPG 24-1: “at least ten calendar days prior to the end date”
Final report due29 Dec 2028in 803 days
award ending 2028-08-31 · Research.gov
PAPPG 24-1: “no later than 120-days following the end date of the award”
Project outcomes report due29 Dec 2028in 803 days
award ending 2028-08-31 · Research.gov
PAPPG 24-1: “no later than 120 days following the end date”
Award is closed out29 Dec 2028in 803 days
award ending 2028-08-31 · Research.gov
PAPPG 24-1: “financially closed out 120 days after their expiration date”

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NSF lists this award's end date as 31 August 2028.
NSF rules say the final report is due no later than 120 days after that.
So the final report is due by 29 December 2028.

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Award card

Award number: 2454140
Period of support: 1 Sep 2025 – 31 Aug 2028
Amount: $549,996
Awardee: The Scripps Research Institute, LA Jolla, CA
Program: CMFP-Chem Mech Funct, and Prop, OFFICE OF MULTIDISCIPLINARY AC, Chemical Synthesis
Directorate: MPS

Abstract

With the support of the Chemical Synthesis and Chemical Mechanism, Function, and Properties Programs in the Division of Chemistry, Professor Ryan Shenvi of The Scripps Research Institute is studying the chemical synthesis and modification of new anti-fungal and anti-malarial medicines based on siccanin, a substance produced by a mold called Helminthosporium siccans Drechsler. The strategy of synthetically altering a…

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