NSF award 2514164 · University of Chicago
BRING-SynBio: Dynamic cooperative binders for endogenously gated cellular control
Final report due
28 January 2028
in 467 days · The award ends on 30 September 2027.
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Dates this award owes
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- Decide about an extension2 Jun 2027in 227 days
award ending 2027-09-30 · Research.gov
- Extension request16 Aug 2027in 302 days
award ending 2027-09-30 · Research.gov
- No-cost extension notice20 Sep 2027in 337 days
award ending 2027-09-30 · Research.gov
- Final report due28 Jan 2028in 467 days
award ending 2027-09-30 · Research.gov
- Project outcomes report due28 Jan 2028in 467 days
award ending 2027-09-30 · Research.gov
- Award is closed out28 Jan 2028in 467 days
award ending 2027-09-30 · Research.gov
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- NSF lists this award's end date as 30 September 2027.
- NSF rules say the final report is due no later than 120 days after that.
- So the final report is due by 28 January 2028.
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Award card
- Award number
- 2514164
- Period of support
- 1 Oct 2025 – 30 Sep 2027
- Amount
- $300,000
- Awardee
- University of Chicago, Chicago, IL
- Program
- Cellular & Biochem Engineering
- Directorate
- ENG
Abstract
Cells sense and respond to their environments. Immune system cells sense and respond to viruses, bacteria, and even cancer cells. Most sense and response circuits involve several intermediate molecules acting as a cascade. This takes time and makes it difficult to engineer these circuits to respond to new inputs or to generate new responses. Existing circuits often overlap and interact. This makes efforts to modify…
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