NSF award 2515799 · Columbia University

MFB: Programmable RNA Targeting and Engineering using Pentatricopeptide Repeat Proteins

Final report due

29 December 2028

in 803 days · The award ends on 31 August 2028.

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award ending 2028-08-31 · Research.gov
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award ending 2028-08-31 · Research.gov
PAPPG 24-1: “at least 45 days prior to the end date”
No-cost extension notice21 Aug 2028in 673 days
award ending 2028-08-31 · Research.gov
PAPPG 24-1: “at least ten calendar days prior to the end date”
Final report due29 Dec 2028in 803 days
award ending 2028-08-31 · Research.gov
PAPPG 24-1: “no later than 120-days following the end date of the award”
Project outcomes report due29 Dec 2028in 803 days
award ending 2028-08-31 · Research.gov
PAPPG 24-1: “no later than 120 days following the end date”
Award is closed out29 Dec 2028in 803 days
award ending 2028-08-31 · Research.gov
PAPPG 24-1: “financially closed out 120 days after their expiration date”

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NSF lists this award's end date as 31 August 2028.
NSF rules say the final report is due no later than 120 days after that.
So the final report is due by 29 December 2028.

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Award card

Award number: 2515799
Period of support: 1 Sep 2025 – 31 Aug 2028
Amount: $1,200,000
Awardee: Columbia University, NEW York, NY
Program: CHEMISTRY PROJECTS, Genetic Mechanisms, OFFICE OF MULTIDISCIPLINARY AC, Cross-BIO Activities
Directorate: MPS

Abstract

With this award, the Molecular Foundations for Biotechnology (MFB) Program is funding Drs. Chaolin Zhang and Harris H. Wang from Columbia University to engineer modular proteins that can be programmed to precisely edit sequences of RNA messages or control the expression of genes encoded in these messenger RNAs in human cells. This project adapts a unique class of plant proteins, called pentatricopeptide repeat (PPR)…

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