NSF award 2525447 · Pennsylvania State Univ University Park

EDGE FGT: Universal viral-based systems to accelerate gene editing research across the taxonomic range of arthropods

Final report due

28 February 2030

in 1,229 days · The award ends on 31 October 2029.

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So the final report is due by 28 February 2030.

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Award card

Award number: 2525447
Period of support: 1 Nov 2025 – 31 Oct 2029
Amount: $2,200,000
Awardee: Pennsylvania State Univ University Park, University Park, PA
Program: EDGE Tools
Directorate: BIO

Abstract

Genetic manipulation is usually performed by injecting gene editing materials into embryos, which is difficult, expensive, and inefficient. We have identified a virus that infects the ovaries and testes of arthropods after injecting them or feeding it to them. When the virus is modified to carry gene editing materials, infected arthropods have genetically modified offspring, a technique that is much easier than…

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