NSF award 2532513 · Regents of the University of Michigan - Ann Arbor
Harnessing Large Protein Dynamics to Control Chemical Transformations
Final report due
28 November 2029
in 1,137 days · The award ends on 31 July 2029.
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Dates this award owes
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- Decide about an extension2 Apr 2029in 897 days
award ending 2029-07-31 · Research.gov
- Extension request16 Jun 2029in 972 days
award ending 2029-07-31 · Research.gov
- No-cost extension notice21 Jul 2029in 1007 days
award ending 2029-07-31 · Research.gov
- Final report due28 Nov 2029in 1137 days
award ending 2029-07-31 · Research.gov
- Project outcomes report due28 Nov 2029in 1137 days
award ending 2029-07-31 · Research.gov
- Award is closed out28 Nov 2029in 1137 days
award ending 2029-07-31 · Research.gov
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How we got this date
- NSF lists this award's end date as 31 July 2029.
- NSF rules say the final report is due no later than 120 days after that.
- So the final report is due by 28 November 2029.
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Award card
- Award number
- 2532513
- Period of support
- 15 Aug 2026 – 31 Jul 2029
- Amount
- $552,000
- Awardee
- Regents of the University of Michigan - Ann Arbor, ANN Arbor, MI
- Program
- Chemistry of Life Processes
- Directorate
- MPS
Abstract
Researchers from the University of Michigan are investigating how a vitamin B12-dependent enzyme orchestrates a series of chemically challenging methyl-transfer reactions essential to human metabolism. Methionine synthase (MS) is a large, multi-domain enzyme that plays a central role in one-carbon metabolism, catalyzing reactions between inherently unreactive molecules that would not proceed under normal…
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