NSF award 2538015 · Noara Therapeutics Corp.

SBIR Phase I: Leveraging Sequence-Structure-Function Relationships to Improve RNA Therapeutics

Final report due

28 October 2027

in 374 days · The award ends on 30 June 2027.

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Decide about an extension2 Mar 2027in 134 days
award ending 2027-06-30 · Research.gov
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Extension request16 May 2027in 209 days
award ending 2027-06-30 · Research.gov
PAPPG 24-1: “at least 45 days prior to the end date”
No-cost extension notice20 Jun 2027in 244 days
award ending 2027-06-30 · Research.gov
PAPPG 24-1: “at least ten calendar days prior to the end date”
Final report due28 Oct 2027in 374 days
award ending 2027-06-30 · Research.gov
PAPPG 24-1: “no later than 120-days following the end date of the award”
Project outcomes report due28 Oct 2027in 374 days
award ending 2027-06-30 · Research.gov
PAPPG 24-1: “no later than 120 days following the end date”
Award is closed out28 Oct 2027in 374 days
award ending 2027-06-30 · Research.gov
PAPPG 24-1: “financially closed out 120 days after their expiration date”

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NSF lists this award's end date as 30 June 2027.
NSF rules say the final report is due no later than 120 days after that.
So the final report is due by 28 October 2027.

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Award card

Award number: 2538015
Period of support: 1 Jul 2026 – 30 Jun 2027
Amount: $305,000
Awardee: Noara Therapeutics Corp., Watertown, MA
Program: SBIR Phase I
Directorate: TIP

Abstract

The broader and commercial impact of this Small Business Innovation Research (SBIR) Phase I project is the development of a new approach for improving the efficacy, durability, and safety of RNA medicines. RNA-based therapies often fail to achieve sustained effects in the body or trigger unwanted immune responses, limiting their usefulness for chronic and serious diseases such as autoimmune disorders, cancer, and…

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