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NSF award 2538091 · Endure Biotherapeutics, INC.

SBIR Phase I: A Novel Precision Microbiome Therapy for Phenylketonuria

Final report due

30 April 2027

in 194 days · The award ends on 31 December 2026.

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Dates this award owes

NSF emails you about this too.

  • Extension request16 Nov 2026in 29 days

    award ending 2026-12-31 · Research.gov

  • No-cost extension notice21 Dec 2026in 64 days

    award ending 2026-12-31 · Research.gov

  • Final report due30 Apr 2027in 194 days

    award ending 2026-12-31 · Research.gov

  • Project outcomes report due30 Apr 2027in 194 days

    award ending 2026-12-31 · Research.gov

  • Award is closed out30 Apr 2027in 194 days

    award ending 2026-12-31 · Research.gov

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How we got this date

  1. NSF lists this award's end date as 31 December 2026.
  2. NSF rules say the final report is due no later than 120 days after that.
  3. So the final report is due by 30 April 2027.

Read the rule on Research.gov

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Award card

Award number
2538091
Period of support
1 Jul 2026 – 31 Dec 2026
Amount
$305,000
Awardee
Endure Biotherapeutics, INC., Carlsbad, CA
Program
SBIR Phase I
Directorate
TIP

Abstract

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project proposed by the small business will develop the proprietary, precision microbiome-based therapeutic platform for Phenylketonuria (PKU) incorporating engineered native bacteria. PKU is a rare inherited metabolic disorder caused by a deficiency of the enzyme phenylalanine hydroxylase, resulting in toxic…

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