NSF award 2540525 · Tulane University

CAREER: From Energy Flow to Function: A Biophysical Framework for Rational Enzyme Evolution

Final report due

28 September 2031

in 1,806 days · The award ends on 31 May 2031.

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PAPPG 24-1: “at least 45 days prior to the end date”
No-cost extension notice21 May 2031in 1676 days
award ending 2031-05-31 · Research.gov
PAPPG 24-1: “at least ten calendar days prior to the end date”
Final report due28 Sep 2031in 1806 days
award ending 2031-05-31 · Research.gov
PAPPG 24-1: “no later than 120-days following the end date of the award”
Project outcomes report due28 Sep 2031in 1806 days
award ending 2031-05-31 · Research.gov
PAPPG 24-1: “no later than 120 days following the end date”
Award is closed out28 Sep 2031in 1806 days
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PAPPG 24-1: “financially closed out 120 days after their expiration date”

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NSF rules say the final report is due no later than 120 days after that.
So the final report is due by 28 September 2031.

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Award card

Award number: 2540525
Period of support: 1 Jun 2026 – 31 May 2031
Amount: $635,950
Awardee: Tulane University, NEW Orleans, LA
Program: Molecular Biosciences
Directorate: BIO

Abstract

Proteins are essential to life and play central roles in medicine, biotechnology, and sustainable manufacturing. They enable critical chemical reactions that support human health, environmental processes, and industrial production. However, improving protein function remains a major challenge because current approaches often rely on trial-and-error methods or static structural information, which do not fully capture…

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