NSF award 2543564 · University of Georgia Research Foundation Inc

CAREER: To Be Nitrated or To Be Crosslinked: Illuminating Unusual Cytochrome P450 Enzymes in RiPP Biosynthesis

Final report due

29 December 2031

in 1,898 days · The award ends on 31 August 2031.

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PAPPG 24-1: “at least ten calendar days prior to the end date”
Final report due29 Dec 2031in 1898 days
award ending 2031-08-31 · Research.gov
PAPPG 24-1: “no later than 120-days following the end date of the award”
Project outcomes report due29 Dec 2031in 1898 days
award ending 2031-08-31 · Research.gov
PAPPG 24-1: “no later than 120 days following the end date”
Award is closed out29 Dec 2031in 1898 days
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PAPPG 24-1: “financially closed out 120 days after their expiration date”

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So the final report is due by 29 December 2031.

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Award card

Award number: 2543564
Period of support: 1 Sep 2026 – 31 Aug 2031
Amount: $700,000
Awardee: University of Georgia Research Foundation Inc, Athens, GA
Program: Chemistry of Life Processes
Directorate: MPS

Abstract

Researchers from the University of Georgia (UGA) are investigating the enzymatic strategies that underpin aromatic nitration and crosslinking reactions during the maturation of ribosomally synthesized and post-translationally modified peptides (RiPPs). RiPPs are an important source of bioactive natural products with significant therapeutic potential, and cytochrome P450 enzymes (CYPs) play central roles in…

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