NSF award 2548055 · University of Colorado at Boulder
Probing the emergence of novel protopathways from underground metabolism
Final report due
28 October 2030
in 1,471 days · The award ends on 30 June 2030.
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- Decide about an extension2 Mar 2030in 1231 days
award ending 2030-06-30 · Research.gov
- Extension request16 May 2030in 1306 days
award ending 2030-06-30 · Research.gov
- No-cost extension notice20 Jun 2030in 1341 days
award ending 2030-06-30 · Research.gov
- Final report due28 Oct 2030in 1471 days
award ending 2030-06-30 · Research.gov
- Project outcomes report due28 Oct 2030in 1471 days
award ending 2030-06-30 · Research.gov
- Award is closed out28 Oct 2030in 1471 days
award ending 2030-06-30 · Research.gov
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- NSF lists this award's end date as 30 June 2030.
- NSF rules say the final report is due no later than 120 days after that.
- So the final report is due by 28 October 2030.
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Award card
- Award number
- 2548055
- Period of support
- 1 Jul 2026 – 30 Jun 2030
- Amount
- $1,058,870
- Awardee
- University of Colorado at Boulder, Boulder, CO
- Program
- Molecular Biosciences
- Directorate
- BIO
Abstract
Protein enzymes catalyze almost every metabolic reaction in all living organisms. Most enzymes are specialized for certain tasks, but most have side activities termed “promiscuous” activities. Promiscuous protein enzyme activities are typically inefficient but are still a million-fold better than chemical activities without protein. Consequently, promiscuous activities provide a good starting point for evolution of…
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