NSF award 2553768 · University of Arkansas
DMS/NIGMS 1: Mathematical and Computational Frameworks for Predicting Mutation-Induced Perturbations in Molecular Recognition
Final report due
29 December 2029
in 1,168 days · The award ends on 31 August 2029.
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Dates this award owes
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- Decide about an extension3 May 2029in 928 days
award ending 2029-08-31 · Research.gov
- Extension request17 Jul 2029in 1003 days
award ending 2029-08-31 · Research.gov
- No-cost extension notice21 Aug 2029in 1038 days
award ending 2029-08-31 · Research.gov
- Final report due29 Dec 2029in 1168 days
award ending 2029-08-31 · Research.gov
- Project outcomes report due29 Dec 2029in 1168 days
award ending 2029-08-31 · Research.gov
- Award is closed out29 Dec 2029in 1168 days
award ending 2029-08-31 · Research.gov
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- NSF lists this award's end date as 31 August 2029.
- NSF rules say the final report is due no later than 120 days after that.
- So the final report is due by 29 December 2029.
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Award card
- Award number
- 2553768
- Period of support
- 1 Sep 2026 – 31 Aug 2029
- Amount
- $599,869
- Awardee
- University of Arkansas, Fayetteville, AR
- Program
- NIGMS, OFFICE OF MULTIDISCIPLINARY AC
- Directorate
- MPS
Abstract
Protein mutations drive disease progression and therapeutic resistance by altering how proteins interact with other molecules in cells. A major scientific challenge is determining how small mutation-induced changes in protein structure and dynamics lead to large changes in biological function and treatment response. Current experimental approaches are often expensive, labor-intensive, and difficult to scale to the…
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