NSF award 2601534 · Princeton University

Chiral Amine Synthesis Using Engineered Pyridoxal-Dependent Enzymes

Final report due

28 November 2029

in 1,137 days · The award ends on 31 July 2029.

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Final report due28 Nov 2029in 1137 days
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PAPPG 24-1: “no later than 120-days following the end date of the award”
Project outcomes report due28 Nov 2029in 1137 days
award ending 2029-07-31 · Research.gov
PAPPG 24-1: “no later than 120 days following the end date”
Award is closed out28 Nov 2029in 1137 days
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So the final report is due by 28 November 2029.

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Award card

Award number: 2601534
Period of support: 15 Aug 2026 – 31 Jul 2029
Amount: $576,000
Awardee: Princeton University, Princeton, NJ
Program: Chemistry of Life Processes
Directorate: MPS

Abstract

Researchers from Princeton University are developing new enzyme catalysts that transform simple amines into complex, chiral molecules used in medicines and agrochemicals. Chiral amines are found in many societally valuable molecules, yet their synthesis often requires multiple chemical steps and expensive catalysts because existing methods separate carbon–carbon bond formation from the creation of molecular…

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