NSF award 2603280 · Van Andel Research Institute

PPM: Functional asymmetries of trans-histone and histone-DNA crosstalk in development

Final report due

28 October 2030

in 1,471 days · The award ends on 30 June 2030.

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Extension request16 May 2030in 1306 days
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PAPPG 24-1: “at least 45 days prior to the end date”
No-cost extension notice20 Jun 2030in 1341 days
award ending 2030-06-30 · Research.gov
PAPPG 24-1: “at least ten calendar days prior to the end date”
Final report due28 Oct 2030in 1471 days
award ending 2030-06-30 · Research.gov
PAPPG 24-1: “no later than 120-days following the end date of the award”
Project outcomes report due28 Oct 2030in 1471 days
award ending 2030-06-30 · Research.gov
PAPPG 24-1: “no later than 120 days following the end date”
Award is closed out28 Oct 2030in 1471 days
award ending 2030-06-30 · Research.gov
PAPPG 24-1: “financially closed out 120 days after their expiration date”

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So the final report is due by 28 October 2030.

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Award card

Award number: 2603280
Period of support: 1 Jul 2026 – 30 Jun 2030
Amount: $1,500,000
Awardee: Van Andel Research Institute, Grand Rapids, MI
Program: Molecular Biosciences
Directorate: BIO

Abstract

Understanding how cells control gene expression is a central challenge in biology. Genes are packaged in chromatin and their expression is controlled by chemical modifications on histone proteins and DNA in nucleosomes, the fundamental building blocks of chromatin. This project examines how complex combinations of histone or DNA modifications that occur asymmetrically within individual nucleosomes work together to…

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