NSF award 2603593 · University of Washington
Direct and Accurate Amide-level Hydrogen/deuterium Exchange Measurements
Final report due
28 November 2029
in 1,137 days · The award ends on 31 July 2029.
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Dates this award owes
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- Decide about an extension2 Apr 2029in 897 days
award ending 2029-07-31 · Research.gov
- Extension request16 Jun 2029in 972 days
award ending 2029-07-31 · Research.gov
- No-cost extension notice21 Jul 2029in 1007 days
award ending 2029-07-31 · Research.gov
- Final report due28 Nov 2029in 1137 days
award ending 2029-07-31 · Research.gov
- Project outcomes report due28 Nov 2029in 1137 days
award ending 2029-07-31 · Research.gov
- Award is closed out28 Nov 2029in 1137 days
award ending 2029-07-31 · Research.gov
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- NSF lists this award's end date as 31 July 2029.
- NSF rules say the final report is due no later than 120 days after that.
- So the final report is due by 28 November 2029.
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Award card
- Award number
- 2603593
- Period of support
- 15 Aug 2026 – 31 Jul 2029
- Amount
- $429,336
- Awardee
- University of Washington, Seattle, WA
- Program
- Chemical Measurement & Imaging
- Directorate
- MPS
Abstract
This grant supports the development of residue-specific resolution Hydrogen/Deuterium exchange with mass spectrometry (HDX-MS), a widespread analytical tool for characterizing proteins. One ongoing limitation with HDX-MS has been that it is inherently a low-resolution technique, often leading to incomplete characterization of protein structure or binding interactions that are critical to understanding how proteins…
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