NSF award 2610006 · California Institute of Technology

NSF-ANR: Unravelling the Critical Role of the Extracellular Matrix in the Functions of the Hypothalamus

Final report due

28 November 2029

in 1,137 days · The award ends on 31 July 2029.

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award ending 2029-07-31 · Research.gov
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award ending 2029-07-31 · Research.gov
PAPPG 24-1: “at least 45 days prior to the end date”
No-cost extension notice21 Jul 2029in 1007 days
award ending 2029-07-31 · Research.gov
PAPPG 24-1: “at least ten calendar days prior to the end date”
Final report due28 Nov 2029in 1137 days
award ending 2029-07-31 · Research.gov
PAPPG 24-1: “no later than 120-days following the end date of the award”
Project outcomes report due28 Nov 2029in 1137 days
award ending 2029-07-31 · Research.gov
PAPPG 24-1: “no later than 120 days following the end date”
Award is closed out28 Nov 2029in 1137 days
award ending 2029-07-31 · Research.gov
PAPPG 24-1: “financially closed out 120 days after their expiration date”

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NSF lists this award's end date as 31 July 2029.
NSF rules say the final report is due no later than 120 days after that.
So the final report is due by 28 November 2029.

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Award card

Award number: 2610006
Period of support: 15 Aug 2026 – 31 Jul 2029
Amount: $540,001
Awardee: California Institute of Technology, Pasadena, CA
Program: PHYSICS OF LIVING SYSTEMS
Directorate: MPS

Abstract

The ECM-MetaboBrain project seeks to understand how the brain controls hunger, blood sugar, and body weight by studying an overlooked component of brain tissue called the extracellular matrix (ECM). Within this matrix are long sugar-like molecules known as glycosaminoglycans (GAGs), which may play a critical role in how brain cells respond to metabolic hormones such as leptin and GLP-1—hormones that regulate…

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