NSF award 2613303 · William Marsh Rice University

Collaborative Research: FDT-BioTech: Advancing Mathematical and Statistical Foundations to Enhance Human Digital Twin of Neurophysiological Modeling and Uncertainty Quantification

Final report due

29 April 2028

in 559 days · The award ends on 31 December 2027.

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Decide about an extension2 Sep 2027in 319 days
award ending 2027-12-31 · Research.gov
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Extension request16 Nov 2027in 394 days
award ending 2027-12-31 · Research.gov
PAPPG 24-1: “at least 45 days prior to the end date”
No-cost extension notice21 Dec 2027in 429 days
award ending 2027-12-31 · Research.gov
PAPPG 24-1: “at least ten calendar days prior to the end date”
Final report due29 Apr 2028in 559 days
award ending 2027-12-31 · Research.gov
PAPPG 24-1: “no later than 120-days following the end date of the award”
Project outcomes report due29 Apr 2028in 559 days
award ending 2027-12-31 · Research.gov
PAPPG 24-1: “no later than 120 days following the end date”
Award is closed out29 Apr 2028in 559 days
award ending 2027-12-31 · Research.gov
PAPPG 24-1: “financially closed out 120 days after their expiration date”

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NSF lists this award's end date as 31 December 2027.
NSF rules say the final report is due no later than 120 days after that.
So the final report is due by 29 April 2028.

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Award card

Award number: 2613303
Period of support: 15 Feb 2026 – 31 Dec 2027
Amount: $549,341
Awardee: William Marsh Rice University, Houston, TX
Program: Engineering of Biomed Systems, STATISTICS, OFFICE OF MULTIDISCIPLINARY AC, CYBERINFRASTRUCTURE
Directorate: MPS

Abstract

This project aims to develop the mathematical foundations for a digital twin (DT) system for individuals with autism spectrum disorder (ASD), focusing on dynamic modeling, prediction, uncertainty quantification, and treatment or intervention recommendation through DT-based optimization. ASD is characterized by challenges in social interaction, communication, and behavior, such as difficulties in forming…

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