NSF award 2622634 · University of Minnesota-Twin Cities

Defining Reproducibility in PURE Cell-Free Expression through Ontological Benchmarking and a Minimal Information Reporting Standard

Final report due

29 December 2027

in 437 days · The award ends on 31 August 2027.

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Decide about an extension3 May 2027in 197 days
award ending 2027-08-31 · Research.gov
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Extension request17 Jul 2027in 272 days
award ending 2027-08-31 · Research.gov
PAPPG 24-1: “at least 45 days prior to the end date”
No-cost extension notice21 Aug 2027in 307 days
award ending 2027-08-31 · Research.gov
PAPPG 24-1: “at least ten calendar days prior to the end date”
Final report due29 Dec 2027in 437 days
award ending 2027-08-31 · Research.gov
PAPPG 24-1: “no later than 120-days following the end date of the award”
Project outcomes report due29 Dec 2027in 437 days
award ending 2027-08-31 · Research.gov
PAPPG 24-1: “no later than 120 days following the end date”
Award is closed out29 Dec 2027in 437 days
award ending 2027-08-31 · Research.gov
PAPPG 24-1: “financially closed out 120 days after their expiration date”

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NSF lists this award's end date as 31 August 2027.
NSF rules say the final report is due no later than 120 days after that.
So the final report is due by 29 December 2027.

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Award card

Award number: 2622634
Period of support: 1 Sep 2026 – 31 Aug 2027
Amount: $195,526
Awardee: University of Minnesota-Twin Cities, Minneapolis, MN
Program: Cross-BIO Activities
Directorate: BIO

Abstract

Cell-free protein synthesis systems offer a flexible platform to study biological processes outside of living cells. Despite their promise, these systems remain difficult to characterize and reproduce across laboratories, limiting their broader adoption and utility. This project will develop a rigorous benchmarking framework for protein expression using recombinantly expressed elements (PURE), a cell-free protein…

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