NSF award 2625206 · University of California-Santa Barbara

Diazeniumdiolate Siderophores: Biosynthesis and Reactivity

Final report due

28 February 2030

in 1,229 days · The award ends on 31 October 2029.

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So the final report is due by 28 February 2030.

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Award card

Award number: 2625206
Period of support: 1 Nov 2026 – 31 Oct 2029
Amount: $587,894
Awardee: University of California-Santa Barbara, Santa Barbara, CA
Program: Chemistry of Life Processes
Directorate: MPS

Abstract

Researchers from the University of California at Santa Barbara are investigating the biosynthesis and reactivity of a newly discovered iron-binding ligand in a class of microbial natural products called siderophores. The new ligand is a diazeniumdiolate present in the amino acid graminine. The biosynthesis of this amino acid involves two new classes of metalloenzymes of potential biotechnological significance. The…

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