NSF award 2529546 · University of Puerto Rico Mayaguez

ISS: Biomanufacturing of Mesenchymal Stem Cell Secretomes for Tissue Regeneration

Final report due

30 March 2029

in 894 days · The award ends on 30 November 2028.

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Decide about an extension2 Aug 2028in 654 days
award ending 2028-11-30 · Research.gov
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Extension request16 Oct 2028in 729 days
award ending 2028-11-30 · Research.gov
PAPPG 24-1: “at least 45 days prior to the end date”
No-cost extension notice20 Nov 2028in 764 days
award ending 2028-11-30 · Research.gov
PAPPG 24-1: “at least ten calendar days prior to the end date”
Final report due30 Mar 2029in 894 days
award ending 2028-11-30 · Research.gov
PAPPG 24-1: “no later than 120-days following the end date of the award”
Project outcomes report due30 Mar 2029in 894 days
award ending 2028-11-30 · Research.gov
PAPPG 24-1: “no later than 120 days following the end date”
Award is closed out30 Mar 2029in 894 days
award ending 2028-11-30 · Research.gov
PAPPG 24-1: “financially closed out 120 days after their expiration date”

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NSF lists this award's end date as 30 November 2028.
NSF rules say the final report is due no later than 120 days after that.
So the final report is due by 30 March 2029.

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Award card

Award number: 2529546
Period of support: 1 Dec 2025 – 30 Nov 2028
Amount: $399,276
Awardee: University of Puerto Rico Mayaguez, Mayaguez, PR
Program: Engineering of Biomed Systems, Special Initiatives
Directorate: ENG

Abstract

Mesenchymal stem cells (MSC) are a special type of cell that can reduce inflammation and help rebuild bone, cartilage, and other muscle and skeletal tissues. MSC can be grown and multiplied outside of the body for use as therapies, but the MSC lose their restorative abilities after being cultured for a long time or in tissues due to disease and aging. One possible cause for this decline is that MSC function is…

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